Hunting for microplastics and chemical pollution in the Arctic

The project involves a scientific expedition along the Greenland coast aboard a vessel coordinated by the Lindblad Expedition in collaboration with the National Geographic Society. The expedition will collect biological samples and water, which will subsequently be processed and analyzed at the laboratories of the Research and Teaching Unit of San Benedetto del Tronto (URDIS).

Development of cebranopadol, a potent dual MOP/NOP agonist, for the treatment of Opioid Use Disorder (OUD)

The objective of the project is the clinical development of Cebranopadol for the treatment of opioid addiction. The project may be funded by the NIH-NIDA, and the study will be conducted in collaboration with Park Therapeutics, the company that holds the property rights to the molecule.

Identification of a molecular scaffold for the development of a PET tracer for purinergic P2X7 receptor for molecular imaging of neuroinflammation in PD

Neuroinflammation plays a pivotal role in the pathogenesis of neurodegeneration in Parkinson's Disease (PD) through the upregulation of proinflammatory factors and microglia activation. The purinergic P2X7 receptor (P2X7R) is among the targets actively investigated as PET biomarkers of neuroinflammation because of its crucial role in microglia activation and expression associated with

Meta-coatings for optical breakdown Mitigation

Optical trains exploited in the various applications using the high power continuous wave lasers suffer severely from the damages due to the extremely high and non-homogeneous energy density distribution. In present project, the possibility of exploiting novel Transition metal oxide functionalized materials and meta-structures to mitigate the breakdown phenomena in these components will be investigated.